+(91) 79 4891 1722

info@ralingtonpharma.com

Technology
  1. Home
  2. About Us
  3. Technology
Very Well Positioned For The Furure

Ralington Pharma offers state-of-the-art, multi-purpose plants with a total volume capacity of 150 kL, which comply with the GMP standard and meet almost all customer requirements.

Pilot Plant Manufacturing

Capacities

  • Reactor volume : 3.3 kL
  • Pressure : 1 mbar to 25 bar
  • Temperature range : -60 °C to +200 °C
  • 7 reactors of 250 l and 630 l (glass-lined, stainless steel)
  • Further processing :
    • Mill
    • Dryer
    • Sieve
    • Packaging
    • Centrifuge and several filters
Multi-Purpose Plant for highly active compounds

Capacities

  • Isolator box
  • Reactor volume : 7.5 m³
  • Separate IPC and QC laboratory
  • Vacuum dryer and hermetic filling
  • Temperature range: -10 °C to +160 °C
  • Reactors with 2.5 m³ of volume, glass-lined
  • Lab capacities for process development and scale-up
  • Temperature-controlled centrifuge with on-site purification
Our Technologies
  • Acylation
  • Cyanation
  • Alkylation
  • Epoxidation
  • Grignard reactions
  • Aldol condensation
  • Diels-Alder reactions
  • Amidation / Amination
  • Friedel-Crafts reaction
  • Halogenation
  • Hydrogenations
    • Metal hydrides : NaBH4, LiAlH4
    • catalytically : H2 with Pd/C, RA-nickel or Pt
  • Reduction
  • Condensation
  • Strecker reaction
  • Mannich reactions
  • Racemat separation
  • Oxidation (e.g. Oppenauer)
  • Organo metallic chemistry with HexLi
  • Esterification
  • Saponification
  • Suzuki coupling
  • Ritter reactions
  • Rearrangement
  • Von Braun reaction
  • Reaction with gases
  • Milling, micronising, sieving
  • Handling of controlled substances and highly potent compounds
  • Handling of corrosive and toxic compounds, e.g. POCl3, SOCl2, NaCN, Br2, HBr, BrCN, methylvinylketone, ethylchloroformiate, epichlorohydrine, NLOST derivatives
GMP kilo lab and second piloting plant

In the year 2019 we will build up a GMP kilo lab and a second piloting plant, where highly potent drugs up to an occupational exposure level (OEL) of less than 1 µg/m³ will be handled safely.

About Us
Top